How dangerous are finasteride and dutasteride?

Finasteride and dutasteride are among the most effective treatments for androgenetic hair loss. At the same time, there are current notices from the EMA (European Medicines Agency), confirming that suicidal thoughts have been reported as an undesirable effect of oral finasteride, especially in the treatment of alopecia. Anyone experiencing low mood, depression, or suicidal thoughts should discontinue finasteride treatment and seek medical advice immediately.

Further points from the notice:

• Sexual dysfunctions can occur and promote mood changes; if signs appear, have them clarified medically and consider discontinuing therapy.
• Because of the same mechanism of action (5-alpha-reductase inhibitors), patients treated with dutasteride should also seek medical advice immediately if mood changes occur.

Conclusion: Finasteride and dutasteride can effectively slow hair loss – but they are prescription medicines with potentially significant side effects. Use belongs in medical hands, with careful counseling and close monitoring.

Classification & alternatives with lower risk

• Topical minoxidil: proven, non-hormonal option. Systemic side effects are less common than with oral 5-AR inhibitors; local irritation is possible.
• ribogrow (cosmetic approach): relies on non-hormonal ingredients and aims to support the scalp. With actives without the hormonal side effects such as those seen with finasteride/dutasteride.

Read more: You can find details on the new risk-minimization measures at EMA:
https://www.ema.europa.eu/en/news/measures-minimise-risk-suicidal-thoughts-finasteride-dutasteride-medicines

This post does not replace medical advice. Please always make therapy decisions together with medical professionals.